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Title   국소진행 위암 및 대장직장암의 수술중방사선치료 ( IORT ) ( Intraoperative Radiation Therapy ( IORT ) in Locally Advanced Gastric and Colorectal Cancer )
Publicationinfo   1992 Jan; 024(04): 596-604.
Key_word   IORT, Locally advanced gastric and colorectal cancer, External irradiation
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Abstract   Local recurence is the most common problem in locally advanced stomach and colorectal cancer even after curative resection. In spite of remarkable improvement of surgical technique, skill of anesthesiology and surportive therapy, reported local recurence is still 50-94% in stomach cancer and 50-100% in colorectal cancer. External irradiation has been advocated for reducing local recurence, but the result is not satisfactory because tumorcidal dose(above 7000 cGy) can not be delivered safely to the high risk-target area without normal tissue damage which may cause unacceptable complication. Intraoperative radiation therapy(IORT) was suggested as a promising modality for reducing local recurence without increasing complication by excluding radiosensitive normal organ (small bowoel, colan) from irradiation field and giving a single high dose with proper electron area on the high risk-target area. Yeunganam University Medical Center started IORT in locally advanced stomach cancer on Jung 15, 1988 and in rectal cnacer on May 30, 1991 as 1st trial in Korea. By May 30, 1992, total 58 cases of stomach cancer and 7 cases of colarectai cancer were entered in IORT protocoL but 54 cases of stomach cancer and 6 cases of colorectal cancer were performed IORT. Five cases were excluded because of advaned stages(3 cases), ealrly stage<1 case) and unexpected machin nary problem(1 case). Eleven cases of 59 who had IORT were dead, because of bleeding (4 cases) in reminant stomach and around anastomosis site which were not included in IORT field, pancreas abscess(1 case) and concinomatoses or peritoneal seeding(5 cases). No definite evidence of local recurence were noted, This suggested us that the effect of IORT in reducing local recurence is satisfactory.
저 자   김명세(Myung Se Kim),김성규(Seong Kyu Kim),송선교(Sun Kyo Song),김재황(Jae Hwang Kim),김홍진(Hong Jin Kim),권굉보(Koing Bo Kwun),김흥대(Heung Dae Kim)